n Medical Technology SA - Neurological features of systemic lupus erythematosus : peer reviewed review

Volume 24, Issue 1
  • ISSN : 1011-5528


Systemic lupus erythematosus (SLE) is a chronic multisystem autoimmune connective tissue disorder, which has variable clinical manifestations that range from mild to life-threatening. Young women between their late teens and early 40s have a much higher prevalence in developing SLE, with a female to male ratio of 9:1. In the United States (U.S.) for example, Lawrence et al. reported that SLE appeared to be more common in black women than in other population groups. One U.S. retrospective study of patient medical records, by McCarty et al. found that the disease was diagnosed 23 times more often in black women. Certain ethnic groups also appear to show a higher prevalence, such as people with Afro - Caribbean or African origin.

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