n Journal of Minimum Intervention in Dentistry - Evaluation of anti-microbial effect and surface morphology of conventional glass ionomer cement and glass ionomer cement containing chlorhexidine - an in vivo study

Volume 3, Issue 1
  • ISSN : 1998-801X


This study compared the antimicrobial effect and surface morphology of glass ionomer cement (GIC) and glass ionomer cement containing 1% W/W Chlorhexidine (GIC+CHX) in vivo. Using split mouth design 32 pairs of mandibular molar teeth with dentin caries were sampled microbiologically using ART method. On the first day, an initial sample was taken from the demineralized dentin followed by a second sample, which was taken from the hard dentin after removal of all soft carious dentin. The cavities were restored with GIC or GIC+CHX. The dentin was re-sampled after 7 days and the cavity subsequently re-restored with respective materials. All samples were processed for microbiological determination of total viable count (TVC), mutans streptococci (MS) and lactobacilli (LB) count. Rubber base impressions were made and the casts poured on after 6 month and 1-year. These casts were analysed for surface morphology under stereomicroscope. The recorded values were statistically analysed using Wilcoxon's signed rank test, Mann-Whitney test and Chi-square test. The results demonstrated considerable antibacterial effect by the GIC and GIC+CHX. The antibacterial activity of GIC+CHX was found to be better than the GIC. There was no clinical difference found for change in surface morphology over the period of 12 months.

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