n Journal of Minimum Intervention in Dentistry - Fluoride release of resin-modified GIC versus fluoride containing composite resin - a quantitative systematic review

Volume 3, Issue 2
  • ISSN : 1998-801X


To assess whether from restorations of comparable size, resin-modified glass ionomer cement releases more fluoride than fluoride containing composite resin.

The trials were identified from a search of the PubMed database on 21 May 2009 using the terms: Glass lonomer Cements"[Mesh] AND "Composite Resins"[Mesh]) AND "Fluorides"[Mesh]. References of accepted articles were checked for additional studies suitable for inclusion.
Prospective 2-arm in-vitro, in-situ or in vivo trials; with relevance to review question including computable data; published in English.
The systematic literature search found 47 trials of which 32 were identified to be in line with the inclusion criteria. Of these, 30 trials (29 in vitro, 1 in vivo) could be traced for review. From the reviewed trials 466 individual datasets were extracted and analyzed.
The overall result of the in vitro trials showed a generally higher fluoride-releasing efficacy of RMGIC than fluoride-containing composite resin. This was not confirmed, however, by the results of the single in-vivo trial, which showed no difference in the fluoride content of plaque adjacent to Class III restoration with either material.
The results of the in vitro trials indicate, that resin-modified glass ionomer cements may have a higher fluoride-releasing efficacy than fluoride-containing composite resin.

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