n Journal of Minimum Intervention in Dentistry - Fluoride release of conventional GIC versus fluoride containing composite resin - a quantitative systematic review

Volume 3, Issue 3
  • ISSN : 1998-801X


to appraise and present detailed quantitative evidence in answer to the review question, whether conventional glass ionomer cement (GIC) releases more fluoride than fluoride containing composite resin.

The trials were identified from a search of the PubMed database on 01 September 2009 using the terms: Search ("Fluorides"[Mesh] AND "Glass Ionomer Cements"[Mesh]) AND "Composite Resins"[Mesh]. References of accepted articles were checked for additional studies suitable for inclusion.
Relevant to review question; Published in English language; 2-arm prospective longitudinal study (in-vitro, in-situ, in-vivo)
The systematic literature search found 317 trials of which 37 were identified to be in line with the inclusion criteria. Of these, 36 in vitro trials could be traced for review. From the reviewed trials, 11 were excluded and 25 accepted. Of these, 163 individual datasets were extracted and analyzed. Of the 163 datasets, 72 were combined in 22 separate meta-analyses and 91 datasets were analyses independently.
The results show that glass-ionomer cements release more fluoride than composite regardless of the type of outcome measured, time period or interval or in which media they were submerged.

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