n Journal of Minimum Intervention in Dentistry - In patients with comparable caries risk, does GIC have a better cariostatic effect then composite? [2008] : grey literature

Volume 7, Issue 3
  • ISSN : 1998-801X


[This document has been captured as part of the JMID-section for Grey-literature. Grey (or gray) literature refers to informally published written material that may be difficult to trace via conventional databases and/or journals as it is not formally published or is not widely accessible. However, Grey literature may still be an important source of information. Examples of grey literature include e.g.: patents, reports, working documents or unpublished manuscripts]

The systematic literature search identified 15 articles in compliance with the broad inclusion criteria. Of these, 6 articles were rejected due to insufficient internal validity. Nine articles were accepted, 1 of which was a systematic review. Eight trials were accepted for data extraction and further meta-analysis. Trials differed in its clinical application of GIC and in the length of study (see section "2. Heterogeneity and META analysis"). The analysis results of dichotomous data showed no difference in caries incidence on tooth tissue adjacent to these materials. The analysis of continuous data showed significant higher microhardness (p=0.0001) and significantly less mineral loss (p=0.0001) of tooth tissue adjacent to GIC after acid attack then tooth tissue adjacent to composite. The findings from continuous data are in line with the results of most rejected trials but not with the conclusions of the accepted systematic reviews by other authors. Further randomized control trials are needed in order to answer the review question more conclusively. It is recommended that reporting of such studies should follow the CONSORT statement.

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