n Journal of Minimum Intervention in Dentistry - Is diabetes associated with the salivary buffer activity? [2008] : grey literature

Volume 7, Issue 4
  • ISSN : 1998-801X


[This document has been captured as part of the JMID-section for Grey- literature. Grey (or gray) literature refers to informally published written material that may be difficult to trace via conventional databases and/or journals as it is not formally published or is not widely accessible. However, Grey literature may still be an important source of information. Examples of grey literature include e.g.: patents, reports, working documents or unpublished manuscripts]

The systematic literature search identified 5 articles in compliance with the broad inclusion criteria. Of these, 1 article was rejected due to insufficient internal validity. Four articles were accepted for data extraction and further meta-analysis. Clinical, methodological and statistical heterogeneity between studies was observed. One further study could not be included for meta-analysis due to missing standard deviation (SD). Meta-analysis was conducted using the remaining 3 articles. The results show a weighted mean difference (WMD) of the buffer capacity between non-diabetics and diabetics of 0.10 (0.07 - 0.14). In light of existing heterogeneity, low number of articles and low weighted mean difference, the result provides an inconclusive answer to the question, whether the saliva buffer capacity is associates with diabetes. In order to answer the review question more studies are needed. It is recommended that such studies should follow the CONSORT and STROBE statements.

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