oa South African Family Practice - Would we prevent asthma with potential therapeutic strategies? : guest editorial
The relationship between early wheezing and subsequent development of asthma is controversial; and the relationship between early childhood viral infection and atopic sensitisation is equally controversial. Additionally, accumulating evidence suggests that susceptibility to viral infection and atopy may derive from a common set of transient developmental defects in cellular immune functions operative during early infancy, which further complicate considerations of causal versus consequential interactions between these disease processes and how they impact on asthma development.
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