oa SA Pharmaceutical Journal - The safety and efficacy of osteoporosis therapy : review

Volume 82, Issue 9
  • ISSN : 2221-5875
  • E-ISSN: 2220-1017



Pharmacological agents used to manage osteoporosis act by decreasing the rate of bone resorption thus slowing down the rate of bone loss, by promoting bone formation, and with the newer generation of medicines, by combining both mechanisms. The aim of treating osteoporosis is to preserve bone mass, restore bone strength and prevent fractures. Although the treatment of osteoporosis is important, its detection and prevention are just as important.. Prevention involves maximising peak adult bone mass and reducing the rate of bone loss. This may be achieved by regular exercise, adequate dietary calcium and vitamin D intake, and the identification and management of risk factors.

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